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Basic Sciences

Basic Sciences

YEAR OF PUBLICATION / RESEARCH TOPIC

2005

The INFIR cohort study: assessment of sensory and motor neuropathy in leprosy at baseline

2005

Use of reverse transcription polymerase chain reaction for the detection of mycobacterium leprae in the slit-skin smears of leprosy patients

2005

The INFIR cohort study: Investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in North India

2008

Detection of viable Mycobacterium leprae in soil samples: insights into possible sources of transmission of leprosy

2008

Early diagnosis of neuropathy in leprosy – comparing diagnostic tests in a large prospective study (the INFIR cohort study)

2009

Genotypic analysis of Mycobacterium leprae strains from different regions of India on the basis of rpoT

2009

Stability of human immunodeficiency virus antibodies in filter paper-spotted serum

2009

Study of cross-reactivity of mycobacterium leprae reactive salivary IgA with other environmental bacteria

2010

Extraction and detection of Mycobacterium leprae DNA from ZNCF-stained skin smear slides for better identification of negative skin smears

2011

Analysis of antibody and cytokine markers for leprosy Nerve damage and reactions in the INFIR cohort in India

2012

Cohort study of the seasonal effect on nasal carriage and the presence of Mycobacterium leprae in an endemic area in the general population

2012

Increased serum circulatory levels of interleukin 17F in type 1reactions of leprosy

2012

Dynamics of Mycobacterium leprae transmission in environmental context: Deciphering the role of environment as a potential reservoir

2013

Single nucleotide polymorphisms typing of Mycobacterium leprae reveals focal transmission of leprosy in high endemic regions of India

2013

Single nucleotide polymorphism-based molecular typing of M. leprae from multicase families of leprosy patients and their surroundings to understand the transmission of leprosy

2013

Interleukin-17F single-nucleotide polymorphism (7488T>C) and its association with susceptibility to leprosy

2013

Cortisol and proinflammatory cytokine profiles in type 1 (reversal) reactions of leprosy

2014

Drug resistance patterns in Mycobacterium leprae isolates from relapsed leprosy patients attending The Leprosy Mission (TLM) hospitals in India

2014

Detection of mycobacterium gilvum first time from the bathing water of leprosy patient from Purulia, West Bengal

2014

A report of rifampin-resistant leprosy from northern and eastern India: identification and in silico analysis of molecular interactions

2015

Report of rpoB mutation in clinically suspected cases of drug resistant leprosy: A study from eastern India

2015

Molecular mimicry between Mycobacterium leprae proteins (50S ribosomal protein L2 and Lysyl-tRNA synthetase) and myelin basic protein: a possible mechanism of nerve damage in leprosy

2015

Genotyping of Mycobacterium leprae strains from a region of high endemic leprosy prevalence in India

2015

Emergence of primary drug resistance to rifampicin in Mycobacterium leprae strains from leprosy patients in India

2015

Comparative evaluation of PCR amplification of RLEP, 16S rRNA, rpoT and Sod A gene targets for detection of M. leprae DNA from clinical and environmental samples

2015

Alpha 1 acid glycoprotein: Increased serum and localized mRNA expression as a monitor for reactions in leprosy

Symposium Report

Symposium on emerging needs in leprosy research in the post elimination era: The Leprosy Mission Trust India

2016

Presence of viable Mycobacterium leprae in environmental specimens around houses Of leprosy patients

2016

Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin

2016

Detection of Mycobacterium gilvum first time from the bathing water of leprosy patient from Purulia, West Bengal

2017

Virtual Screening of Interaction of rpoB gene to Secondary-Line Anti- Leprosy Drugs for Rifampicin Resistant M. leprae using In-Silico Approach

2018

Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-2015

2018

Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins

2018

Detection of Mycobacterium lepromatosis in patients with leprosy in India

2018

Elimination of leprosy in India: An analysis

2018

Enriched whole genome sequencing identified compensatory mutations in the Rna polymerase gene of rifampicin-resistant Mycobacterium leprae strains

2018

Paucibacillary Leprosy: Reappraisal using Ziehl-Neelsen staining of slit skin smears and 16S rRNA Real Time Polymerase Chain Reaction of nasal swabs

2018

Molecular detection of multidrug-resistant Mycobacterium leprae from
Indian leprosy patients

2018

VDR polymorphism, gene expression and vitamin D levels in leprosy patients from North Indian population

2018

Relapse and Drug Resistance in Leprosy: Present Scenario and Critical Issue

2019

Association of non-tuberculous mycobacteria with Mycobacterium leprae in environment of leprosy endemic regions in India

2019

Brain and Spinal Cord Lesions in Leprosy: A Magnetic Resonance Imaging–Based Study

2019

Late reversal reaction with resistant Mycobacterium leprae: an emerging paradigm

2019

Molecular Characterization of Environmental Mycobacterial Species from Leprosy Endemic Tribal Regions of North Purulia District, West Bengal

2019

Multidrug Resistance as a Cause of Steroid‑Nonresponsive Downgrading Type I Reaction in Hansen’s Disease

2019

Resistance as a cause for chronic steroid dependent ENL – a novel paradigm with potential implications in management

2019

Successful treatment of rifampicin resistant case of leprosy by WHO recommended ofloxacin and minocycline regimen

2019

Survival of Mycobacterium leprae and association with Acanthamoeba from environmental samples in the inhabitant areas of active leprosy cases: A cross sectional study from endemic pockets of Purulia, West Bengal

2019

Utility of multiplex PCR for early diagnosis and household contact surveillance for leprosy

2020

Evidence for Mycobacterium leprae Drug Resistance in a Large Cohort of Leprous Neuropathy Patients from India

2020

Neuroimaging in leprosy: The nerves and beyond

2020

Late Leprosy Reaction Presenting as Erythema Multiforme‑Like Erythema Nodosum Leprosum with Underlying Rifampicin Resistance and its Potential Implications

2020

Analysis of bacteriological Index between fixed multidrug therapy and new WHO recommended alternative regimen with ofloxacin, minocycline and clofazimine of rifampicin resistant cases from the hospitals of The Leprosy Mission, India.

2020

Real-time PCR-based quantitation of viable Mycobacterium leprae strain from clinical samples and environmental sources and its genotype in multi-case leprosy families of India

2021

Drug resistance to rifampicin in a case of steroid-dependent erythema nodosum leprosum and the therapeutic implications of resistance and reactions in leprosy

2021

Mimicking B and T cell epitopes between Mycobacterium leprae and host as predictive biomarkers in type 1 reaction in leprosy

2021

Drug Resistance in Mycobacterium Leprae in the Context of Zero Leprosy

2021

Equal rates of drug resistance in leprosy cases with relapse and recurrent /chronic type 2 reaction; Time to revise the guidelines for drug resistance testing in leprosy

2022

Efficacy of fixed duration multidrug therapy for the treatment of multibacillary leprosy: A prospective observational study from Northern India

2022

Existence of viable Mycobacterium leprae in natural environment and its genetic profiling in a leprosy endemic region

2022

High Prevalence of Resistance to Anti‑Leprosy Drugs in Leprosy Cases with Chronic Erythema Nodosum Leprosum: A Matter of Concern

2022

Ofloxacin resistance in multibacillary new leprosy cases from Purulia, West Bengal: a threat to effective secondary line treatment for rifampicin-resistant leprosy cases

2022

Corroboration of cross-reactivity between Mycobacterium leprae and hosts’ salivary and cutaneous proteins: A hope for prognostic biomarkers for the pathogenesis of reactions in leprosy

2022

A prospective case control study of resistance to rifampicin, dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions

2023

A prospective case control study of resistance to rifampicin,dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions

2023

National Guidelines for Surveillance for Antimicrobial Resistance in Leprosy

2023

Diagnosis of Leprosy: Current Updates and Future Directions

2023

Modern molecular era of the mycobacterial world: Insights into diagnosis and transmission of mycobacteria and associated diseases

2023

Editorial: Modern molecular era of the mycobacterial world: Insights into diagnosis and transmission of mycobacteria and associated diseases

2023

Effective amelioration of the Lucio phenomenon with adjuvant tofacitinib therapy in a patient with dual infection of Mycobacterium leprae and Mycobacterium lepromatosis: a case report from India

2023

Efficacy of fixed duration multidrug therapy for the treatment of multibacillary leprosy: A prospective observational study from Northern India

2023

High frequency of ofloxacin resistance patterns of M. leprae from India: An indication to revisit second line anti-leprosy treatment regimen

2023

Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report